Name | N-Acetylethanolamine |
Synonyms | Acetamide MEA Lipamide MEAA Acetylcolamine N-Acetylethanolamine 2-acetylamino-ethanol Mackamide AME-75, AME-100 n-(2-hydroxyethyl)-acetamid N-(2-Hydroxyethyl)acetamide N-(beta-Hydroxyethyl)acetamide 2-(Acetamido)ethanol~N-(2-Hydroxyethyl)acetamide |
CAS | 142-26-7 |
EINECS | 205-530-8 |
InChI | InChI=1/C4H9NO2/c1-4(7)5-2-3-6/h6H,2-3H2,1H3,(H,5,7) |
InChIKey | PVCJKHHOXFKFRP-UHFFFAOYSA-N |
Molecular Formula | C4H9NO2 |
Molar Mass | 103.12 |
Density | 1.12 g/mL at 25 °C (lit.) |
Melting Point | 15.8 °C |
Boling Point | 151-155 °C/5 mmHg (lit.) |
Flash Point | 350°F |
Water Solubility | Soluble in water, 1e+006 mg/L @ 25°C (est), soluble in alcohol and ether. |
Vapor Presure | 0.368-10.5Pa at 25-70℃ |
Appearance | Liquid |
Color | Clear white to yellow |
pKa | 14.56±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.472(lit.) |
Physical and Chemical Properties | N-acetylethanolamine is a colorless slurry-like liquid that is soluble in water, alcohols and ethers. There is a similar odor of pyridine. Melting point 15.8 ℃, boiling point 166-167 ℃(1.07kPa), relative density 1.1079(20/4 ℃), refractive index 1.4370. |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 2 |
RTECS | AC3120000 |
TSCA | Yes |
HS Code | 29241990 |
LogP | -0.117 at 22.2℃ and pH5.4 |
surface tension | 72.1mN/m at 1g/L and 21.4 ℃ |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Application | used in cosmetics industry as antistatic agent, foam enhancer, hair conditioning humectant, skin conditioning surfactants and viscosity control agents. It is a non-sticky glycerin substitute that can be used for skin and hair care. It has moisturizing and lubricating properties and can be used in shampoos, care products and hair conditioners. |
uses | N-acetylethanolamine can be used in dye synthesis and in pharmaceuticals. |
production method | ethanolamine is reacted with methyl acetate. This reaction was carried out at reflux in a water bath for 6h and then subjected to fractional distillation under reduced pressure to give the product N-acetylethanolamine. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |